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Extra Merkel Cell Carcinoma Treatment Ify . Patients with merkel cell carcinoma are usually first treated with surgery. 5 surgery surgery is often used. (A, B) Progressive Merkel cell carcinoma involving the scalp prior to from www.researchgate.net Merkel cell skin cancer after treatment get information about how to live well after merkel cell skin cancer treatment and make decisions about next steps. Merkel cell carcinoma (mcc) is a rare and aggressive skin cancer associated with advanced age and immunosuppression. Merkel cell carcinoma treatment options include surgery, radiation therapy, and chemotherapy.